The PROMIS profile instruments are a collection of short forms containing a fixed number of items from seven PROMIS domains (depression, anxiety, physical function, pain interference, fatigue, sleep disturbance, and ability to participate in social roles and activities). There are three PROMIS Profile Forms: PROMIS-29, PROMIS-43, and PROMIS-57. The profiles are universal rather than disease-specific. They assess all domains over the past seven days except for Physical Function which has no timeframe specified (Huang et al., 2018).
The PROMIS-29 assesses each of the 7 domains with 4 questions with an additional pain intensity numeric rating scale (NRS) i.e. question 29 of the score. The PROMIS measures have been tested and validated in large reference populations making them suitable for research on different conditions (Health Measures).
The PROMIS-29 and its subdomains have been validated and/or cross-walked to a host of legacy measures in a variety of populations, including the Oswestry Disability Index, Roland-Morris Disability Questionnaire, Brief Pain Inventory-Pain Interference domain, the EuroQol Research Foundation five-dimension (EQ-5D) instrument, and quality-adjusted life-year calculations (Pope et al., 2020).